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Lyso-Gb3 modulates the gut microbiota and decreases butyrate production

Fabry disease is a rare X-linked lysosomal storage disorder resulting from deficient activity of α-galactosidase A, leading to the accumulation of glycosphingolipids such as globotriaosylsphingosine (lyso-Gb3). The gastrointestinal symptoms of this disease may be disabling, and the life expectancy o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aguilera-Correa, John-Jairo, Madrazo-Clemente, Patricia, Martínez-Cuesta, María del Carmen, Peláez, Carmen, Ortiz, Alberto, Dolores Sánchez-Niño, María, Esteban, Jaime, Requena, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700068/
https://ncbi.nlm.nih.gov/pubmed/31427622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48426-4
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