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shRNA-interfering LSD1 inhibits proliferation and invasion of gastric cancer cells via VEGF-C/PI3K/AKT signaling pathway

BACKGROUND: Histone Lysine Specific Demethylase 1 (LSD1) is the first histone demethylase to be discovered, which regulates various biological functions by making lysine of histone H3K4, H3K9 and non-histone substrates demethylated. Abnormal regulation of LSD1 is closely related to the occurrence an...

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Bibliographic Details
Published in:World J Gastrointest Oncol
Main Authors: Pan, Hong-Ming, Lang, Wei-Ya, Yao, Li-Jie, Wang, Yan, Li, Xiao-Ling
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700030/
https://ncbi.nlm.nih.gov/pubmed/31435463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v11.i8.622
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