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Micropatterned substrates with physiological stiffness promote cell maturation and Pompe disease phenotype in human induced pluripotent stem cell-derived skeletal myocytes

Recent advances in bioengineering have enabled cell culture systems that more closely mimic the native cellular environment. Here we demonstrated that human induced pluripotent stem cell (iPSC)-derived myogenic progenitors formed highly-aligned myotubes and contracted when seeded on two-dimensional...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Jiwlawat, Nunnapas, Lynch, Eileen M., Napiwocki, Brett N., Stempien, Alana, Ashton, Randolph S., Kamp, Timothy J, Crone, Wendy C., Suzuki, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699746/
https://ncbi.nlm.nih.gov/pubmed/31131875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27075
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