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A CALL TO ARMS: TARGETING THE PAX3-FOXO1 GENE IN ALVEOLAR RHABDOMYOSARCOMA*

INTRODUCTION: Expression of fusion oncoproteins generated by recurrent chromosomal translocations represents a major tumorigenic mechanism characteristic of multiple cancers, including one-third of all sarcomas. Oncogenic fusion genes provide novel targets for therapeutic intervention. The PAX3-FOXO...

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Bibliografski detalji
Izdano u:Expert Opin Ther Targets
Glavni autori: Olanich, Mary E., Barr, Frederic G.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699745/
https://ncbi.nlm.nih.gov/pubmed/23432728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.772136
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