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Peglated-H1/pHGFK1 nanoparticles enhance anti-tumor effects of sorafenib by inhibition of drug-induced autophagy and stemness in renal cell carcinoma

BACKGROUND: Tumor targeting small molecular inhibitors are the most popular treatments for many malignant diseases, including cancer. However, the lower clinical response and drug resistance still limit their clinical efficacies. HGFK1, the first kringle domain of hepatocyte growth factor, has been...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Exp Clin Cancer Res
Main Authors: Gao, Xiaoge, Jiang, Pin, Zhang, Qian, Liu, Qian, Jiang, Shuangshuang, Liu, Ling, Guo, Maomao, Cheng, Qian, Zheng, Junnian, Yao, Hong
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699135/
https://ncbi.nlm.nih.gov/pubmed/31426831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1348-z
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