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How protein binding sensitizes the nucleosome to histone H3K56 acetylation
The nucleosome, the fundamental gene-packing unit comprising an octameric histone protein core wrapped around by DNA, has a flexible structure that enables dynamic gene regulation mechanisms. Histone lysine acetylation at H3K56 removes a positive charge from the histone core where it interacts with...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6698890/ https://ncbi.nlm.nih.gov/pubmed/30768236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00018 |
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