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Therapeutic and Diagnostic Antibodies to CD146: Thirty Years of Research on Its Potential for Detection and Treatment of Tumors

CD146 (MCAM, MUC18, S-Endo1) is a transmembrane glycoprotein belonging to both CAM and mucin families. It exists as different splice variants and is cleaved from the membrane by metalloproteases to generate a soluble form. CD146 is expressed by numerous cancer cells as well as being one of the numer...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Antibodies (Basel)
Hauptverfasser: Stalin, Jimmy, Nollet, Marie, Dignat-George, Françoise, Bardin, Nathalie, Blot-Chabaud, Marcel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698816/
https://ncbi.nlm.nih.gov/pubmed/31548532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib6040017
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