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The Pyrin Inflammasome in Health and Disease
The pyrin inflammasome has evolved as an innate immune sensor to detect bacterial toxin-induced Rho guanosine triphosphatase (Rho GTPase)-inactivation, a process that is similar to the “guard” mechanism in plants. Rho GTPases act as molecular switches to regulate a variety of signal transduction pat...
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| Published in: | Front Immunol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6698799/ https://ncbi.nlm.nih.gov/pubmed/31456795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01745 |
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