FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences

The growing prevalence of deadly microbes with resistance to previously life-saving drug therapies is a dire threat to human health. Detection of low abundance pathogen sequences remains a challenge for metagenomic Next Generation Sequencing (NGS). We introduce FLASH (Finding Low Abundance Sequences...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Quan, Jenai, Langelier, Charles, Kuchta, Alison, Batson, Joshua, Teyssier, Noam, Lyden, Amy, Caldera, Saharai, McGeever, Aaron, Dimitrov, Boris, King, Ryan, Wilheim, Jordan, Murphy, Maxwell, Ares, Lara Pesce, Travisano, Katherine A, Sit, Rene, Amato, Roberto, Mumbengegwi, Davis R, Smith, Jennifer L, Bennett, Adam, Gosling, Roly, Mourani, Peter M, Calfee, Carolyn S, Neff, Norma F, Chow, Eric D, Kim, Peter S, Greenhouse, Bryan, DeRisi, Joseph L, Crawford, Emily D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698650/
https://ncbi.nlm.nih.gov/pubmed/31114866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz418
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