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CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors
A nonsense mutation is a substitutive mutation in a DNA sequence that causes a premature termination during translation and produces stalled proteins, resulting in dysfunction of a gene. Although it usually induces severe genetic disorders, there are no definite methods for inducing read through of...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6698196/ https://ncbi.nlm.nih.gov/pubmed/31164261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.05.013 |
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