1,25-Dihydroxyvitamin D3 Prevents Epithelial-Mesenchymal Transition of HMrSV5 Human Peritoneal Mesothelial Cells by Inhibiting Histone Deacetylase 3 (HDAC3) and Increasing Vitamin D Receptor (VDR) Expression Through the Wnt/β-Catenin Signaling Pathway

BACKGROUND: Peritoneal dialysis is the most common treatment for end-stage renal disease. However, peritoneal fibrosis resulting from long-term peritoneal dialysis restricts peritoneal ultrafiltration. Previous studies have shown a role for 1,25-dihydroxyvitamin D3 (1,25[OH](2)D3) in preventing fibr...

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Detalles Bibliográficos
Publicado en:Med Sci Monit
Main Authors: Liu, Kang-Han, Fu, Jia, Zhou, Nan, Yin, Wei, Yang, Yi-Ya, Ouyang, Sha-Xi, Liang, Yu-Mei
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2019
Assuntos:
Lab/In Vitro Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698096/
https://ncbi.nlm.nih.gov/pubmed/31391414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.916313
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