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miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt–β-catenin pathway

BACKGROUND: MicroRNAs (miRNAs) play crucial roles in tumor initiation and development. Previously, we indicated that miR-504 is downregulated and suppresses tumor proliferation in glioblastoma (GBM). However, the regulation and relevant mechanism of miR-504 in GBM mesenchymal (ME) transition remain...

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書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: Liu, Qiang, Guan, Yanlei, Li, Zhenhang, Wang, Yao, Liu, Yu, Cui, Run, Wang, Yunjie
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697940/
https://ncbi.nlm.nih.gov/pubmed/31419987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1370-1
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