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Universal amplification-free molecular diagnostics by billion-fold hierarchical nanofluidic concentration

Rapid and reliable detection of ultralow-abundance nucleic acids and proteins in complex biological media may greatly advance clinical diagnostics and biotechnology development. Currently, nucleic acid tests rely on enzymatic processes for target amplification (e.g., PCR), which have many inherent i...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ouyang, Wei, Han, Jongyoon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697892/
https://ncbi.nlm.nih.gov/pubmed/31358642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904513116
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