Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy

ELAC2 is a ubiquitously expressed enzyme potentially involved in tRNA processing and cell signaling pathways. Mutations of the ELAC2 gene have been found to confer increased prostate cancer susceptibility in families. ELAC2 protein expression was analyzed by immunohistochemistry in 9,262 patients an...

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Vydáno v:Oncotarget
Hlavní autoři: Schroeder, Cornelia, Navid-Hill, Elham, Meiners, Jan, Hube-Magg, Claudia, Kluth, Martina, Makrypidi-Fraune, Georgia, Simon, Ronald, Büscheck, Franziska, Luebke, Andreas M., Goebel, Cosima, Lang, Dagmar S., Weidemann, Sören, Neubauer, Emily, Hinsch, Andrea, Jacobsen, Frank, Lebok, Patrick, Michl, Uwe, Pehrke, Dirk, Huland, Hartwig, Graefen, Markus, Schlomm, Thorsten, Sauter, Guido, Höflmayer, Doris
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697635/
https://ncbi.nlm.nih.gov/pubmed/31452838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27132
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