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Design and evaluation of an external control arm using prior clinical trials and real-world data
IMPORTANCE: The use of existing data (real world data or prior trials) to design and analyze clinical studies has the potential to accelerate drug development processes and can contribute to rigorous examination of new treatments. OBJECTIVE: We discuss designs and interpretable metrics of bias and s...
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| Опубликовано в: : | Clin Cancer Res |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697596/ https://ncbi.nlm.nih.gov/pubmed/31175098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0820 |
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