A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity

In the Caenorhabditis elegans germline, fem-3 Binding Factor (FBF) partners with LST-1 to maintain stem cells. A crystal structure of an FBF-2/LST-1/RNA complex revealed that FBF-2 recognizes a short RNA motif different from the characteristic 9-nt FBF binding element, and compact motif recognition...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Qiu, Chen, Bhat, Vandita D, Rajeev, Sanjana, Zhang, Chi, Lasley, Alexa E, Wine, Robert N, Campbell, Zachary T, Hall, Traci M Tanaka
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697444/
https://ncbi.nlm.nih.gov/pubmed/31397673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48968
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