Batroxobin accelerated tissue repair via neutrophil extracellular trap regulation and defibrinogenation in a murine ischemic hindlimb model

Batroxobin, isolated from Bothrops moojeni, is a defibrinogenating agent used as a thrombin-like serine protease against fibrinogen for improving microcirculation. Here, we investigated whether, and if so, how batroxobin restores ischemic tissue injury in terms of anti-inflammatory effects. In an in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Masuda, Haruchika, Sato, Atsuko, Shizuno, Tomoko, Yokoyama, Keiko, Suzuki, Yusuke, Tokunaga, Masayoshi, Asahara, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697371/
https://ncbi.nlm.nih.gov/pubmed/31419236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220898
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