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Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge

INTRODUCTION: The sponging of microRNAs by a long non-coding RNA (lncRNA) away from their coding gene targets is a conceptually-simple, yet biologically-complex method of lncRNA-mediated gene regulation. Currently, predictions of genes that participate in sponge-based regulation are largely based on...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Marshall, Erin A., Stewart, Greg L., Sage, Adam P., Lam, Wan L., Brown, Carolyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697314/
https://ncbi.nlm.nih.gov/pubmed/31419261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221371
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