A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

A database of 91 chemicals with published data from both transgenic rodent mutation (TGR) and rodent comet assays has been compiled. The objective was to compare the sensitivity of the two assays for detecting genotoxicity. Critical aspects of study design and results were tabulated for each dataset...

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Publicado en:Mutat Res Genet Toxicol Environ Mutagen
Autores principales: Kirkland, David, Levy, Dan D., LeBaron, Matthew J., Aardema, Marilyn J., Beevers, Carol, Bhalli, Javed, Douglas, George R., Escobar, Patricia A., Farabaugh, Christopher S., Guerard, Melanie, Johnson, George E., Kulkarni, Rohan, Curieux, Frank Le, Long, Alexandra S., Lott, Jasmin, Lovell, David P., Luijten, Mirjam, Marchetti, Francesco, Nicolette, John J., Pfuhler, Stefan, Roberts, Daniel J., Stankowski, Leon F., Thybaud, Veronique, Weiner, Sandy K., Williams, Andrew, Witt, Kristine L., Young, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697155/
https://ncbi.nlm.nih.gov/pubmed/30744809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2019.01.007
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