Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome

To study the role of L-type voltage-gated Ca(++) channels in oligodendrocyte development, we used a mouse model of Timothy syndrome (TS) in which a gain-of-function mutation in the α1 subunit of the L-type Ca(++) channel Cav1.2 gives rise to an autism spectrum disorder (ASD). Oligodendrocyte progeni...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Glia
Prif Awduron: Cheli, Veronica T., Santiago González, Diara A., Zamora, Norma N., Lama, Tenzing N., Spreuer, Vilma, Rasmusson, Randall L., Bett, Glenna C., Panagiotakos, Georgia, Paez, Pablo M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697123/
https://ncbi.nlm.nih.gov/pubmed/30151840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23468
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