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High-Throughput Screening and Quantitative Chemical Ranking for Sodium Iodide Symporter (NIS) Inhibitors in ToxCast Phase I Chemical Library

Thyroid uptake of iodide via the sodium-iodide symporter (NIS) is the first step in the biosynthesis of thyroid hormones that are critical for health and development in humans and wildlife. Despite having long been a known target of endocrine disrupting chemicals such as perchlorate, information reg...

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Detalhes bibliográficos
Publicado no:Environ Sci Technol
Main Authors: Wang, Jun, Hallinger, Daniel R., Murr, Ashley S., Buckalew, Angela R., Simmons, Steven O., Laws, Susan C., Stoker, Tammy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697091/
https://ncbi.nlm.nih.gov/pubmed/29611697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.7b06145
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