Light Stress-Induced Increase of Sphingosine 1-Phosphate in Photoreceptors and Its Relevance to Retinal Degeneration

Sphingosine 1-phosphate (S1P) is a potent lipid mediator that modulates inflammation and angiogenesis. In this study, we investigated the possible involvement of S1P in the pathology of light-induced retinal degeneration in vivo and in vitro. The intracellular S1P and sphingosine kinase (SphK) activ...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Terao, Ryo, Honjo, Megumi, Ueta, Takashi, Obinata, Hideru, Izumi, Takashi, Kurano, Makoto, Yatomi, Yutaka, Koso, Hideto, Watanabe, Sumiko, Aihara, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696268/
https://ncbi.nlm.nih.gov/pubmed/31357484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153670
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