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Structural Mapping of Missense Mutations in the Pex1/Pex6 Complex

Peroxisome biogenesis disorders (PBDs) are nontreatable hereditary diseases with a broad range of severity. Approximately 65% of patients are affected by mutations in the peroxins Pex1 and Pex6. The proteins form the heteromeric Pex1/Pex6 complex, which is important for protein import into peroxisom...

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Pubblicato in:Int J Mol Sci
Autori principali: Schieferdecker, Anne, Wendler, Petra
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696164/
https://ncbi.nlm.nih.gov/pubmed/31374812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153756
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