Downregulation of STAT3, β-Catenin, and Notch-1 by Single and Combinations of siRNA Treatment Enhance Chemosensitivity of Wild Type and Doxorubicin Resistant MCF7 Breast Cancer Cells to Doxorubicin

Combinatorial therapeutic strategies using siRNA and small molecules to eradicate tumors are emerging. Targeting multiple signaling pathways decreases the chances of cancer cells switching and adapting new signaling processes that may occur when using a single therapeutic modality. Aberrant function...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Alshaer, Walhan, Alqudah, Dana A., Wehaibi, Suha, Abuarqoub, Duaa, Zihlif, Malek, Hatmal, Ma’mon M., Awidi, Abdalla
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696135/
https://ncbi.nlm.nih.gov/pubmed/31357721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153696
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