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Synthesis and In Vitro Screening of Novel Heterocyclic β-d-Gluco- and β-d-Galactoconjugates as Butyrylcholinesterase Inhibitors

The development of selective butyrylcholinesterase (BChE) inhibitors may improve the treatment of Alzheimer’s disease by increasing lower synaptic levels of the neurotransmitter acetylcholine, which is hydrolysed by acetylcholinesterase, as well as by overexpressed BChE. An increase in the synaptic...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Baumann, Krešimir, Kordić, Lorena, Močibob, Marko, Šinko, Goran, Tomić, Srđanka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695897/
https://ncbi.nlm.nih.gov/pubmed/31382668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152833
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