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Why Does the Type of Halogen Atom Matter for the Radiosensitizing Properties of 5-Halogen Substituted 4-Thio-2′-Deoxyuridines?

Radiosensitizing properties of substituted uridines are of great importance for radiotherapy. Very recently, we confirmed 5-iodo-4-thio-2′-deoxyuridine (ISdU) as an efficient agent, increasing the extent of tumor cell killing with ionizing radiation. To our surprise, a similar derivative of 4-thio-2...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Spisz, Paulina, Zdrowowicz, Magdalena, Makurat, Samanta, Kozak, Witold, Skotnicki, Konrad, Bobrowski, Krzysztof, Rak, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695862/
https://ncbi.nlm.nih.gov/pubmed/31382376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152819
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