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Formation Mechanism of Ion Channel in Channelrhodopsin-2: Molecular Dynamics Simulation and Steering Molecular Dynamics Simulations

Channelrhodopsin-2 (ChR2) is a light-activated and non-selective cationic channel protein that can be easily expressed in specific neurons to control neuronal activity by light. Although ChR2 has been extensively used as an optogenetic tool in neuroscience research, the molecular mechanism of cation...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yang, Ting, Zhang, Wenying, Cheng, Jie, Nie, Yanhong, Xin, Qi, Yuan, Shuai, Dou, Yusheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695816/
https://ncbi.nlm.nih.gov/pubmed/31382458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153780
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