Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts

Arginine vasopressin (AVP) mediates water reabsorption in the kidney collecting ducts through regulation of aquaporin-2 (AQP2). Also, estrogen has been known to regulate AQP2. Consistently, we previously demonstrated that tamoxifen (TAM), a selective estrogen receptor modulator, attenuates the downr...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Tingskov, Stine Julie, Choi, Hyo-Jung, Holst, Mikkel R., Hu, Shan, Li, Chunling, Wang, Weidong, Frøkiær, Jørgen, Nejsum, Lene N., Kwon, Tae-Hwan, Nørregaard, Rikke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695565/
https://ncbi.nlm.nih.gov/pubmed/31447686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00948
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