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Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning

Semaphorin ligands and their plexin receptors are one of the major cell guidance factors that trigger localised changes in the cytoskeleton. Binding of semaphorin homodimer to plexin brings two plexins in close proximity which is a prerequisite for plexin signalling. This model appears to be too sim...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Rozbesky, Daniel, Robinson, Ross A., Jain, Vitul, Renner, Max, Malinauskas, Tomas, Harlos, Karl, Siebold, Christian, Jones, E. Yvonne
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695400/
https://ncbi.nlm.nih.gov/pubmed/31417095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11683-y
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