Prospective evaluation of two screening methods for molecular testing of metastatic melanoma: Diagnostic performance of BRAF V600E immunohistochemistry and of a NRAS-BRAF fully automated real-time PCR-based assay

Screening for theranostic biomarkers is mandatory for the therapeutic management of cutaneous melanoma. BRAF and NRAS genes must be tested in routine clinical practice. The methods used to identify these alterations must be sensitive to detect mutant alleles in a background of wild type alleles, and...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Vallée, Audrey, Denis-Musquer, Marie, Herbreteau, Guillaume, Théoleyre, Sandrine, Bossard, Céline, Denis, Marc G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695223/
https://ncbi.nlm.nih.gov/pubmed/31415669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221123
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