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Bipartite interface of the measles virus phosphoprotein X domain with the large polymerase protein regulates viral polymerase dynamics

Measles virus (MeV) is a highly contagious, re-emerging, major human pathogen. Replication requires a viral RNA-dependent RNA polymerase (RdRP) consisting of the large (L) polymerase protein complexed with the homo-tetrameric phosphoprotein (P). In addition, P mediates interaction with the nucleopro...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Du Pont, Venice, Jiang, Yi, Plemper, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695210/
https://ncbi.nlm.nih.gov/pubmed/31381607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007995
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