Genetic and clinical predictors of CD4 lymphocyte recovery during suppressive antiretroviral therapy: Whole exome sequencing and antiretroviral therapy response phenotypes

Increase of peripheral blood CD4 lymphocyte counts is a key goal of combined antiretroviral therapy (cART); most, but not all, recipients respond adequately and promptly. A small number of studies have examined specific genetic factors associated with the extent of CD4 recovery. We report a genome-w...

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Veröffentlicht in:PLoS One
Hauptverfasser: Greenblatt, Ruth, Bacchetti, Peter, Boylan, Ross, Kober, Kord, Springer, Gayle, Anastos, Kathryn, Busch, Michael, Cohen, Mardge, Kassaye, Seble, Gustafson, Deborah, Aouizerat, Bradley
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695188/
https://ncbi.nlm.nih.gov/pubmed/31415590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219201
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