MicroRNA-27 inhibits adipogenic differentiation in orbital fibroblasts from patients with Graves’ orbitopathy

BACKGROUND: To investigate the role of microRNA (miR)-27a and miR-27b in adipogenesis in an in vitro model of Graves’ orbitopathy (GO). METHODS: Orbital fat tissues were harvested from GO and non-GO participants for primary orbital fibroblast cultures. The expression levels of miR-27a and miR-27b be...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jang, Sun Young, Chae, Min Kyung, Lee, Joon H., Lee, Eun Jig, Yoon, Jin Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695164/
https://ncbi.nlm.nih.gov/pubmed/31415657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221077
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