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Progeny Varicella-Zoster Virus Capsids Exit the Nucleus but Never Undergo Secondary Envelopment during Autophagic Flux Inhibition by Bafilomycin A1

Varicella-zoster virus (VZV) is an alphaherpesvirus that lacks the herpesviral neurovirulence protein ICP34.5. The underlying hypothesis of this project was that inhibitors of autophagy reduce VZV infectivity. We selected the vacuolar proton ATPase inhibitor bafilomycin A1 for analysis because of it...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Girsch, James H., Walters, Katherine, Jackson, Wallen, Grose, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694825/
https://ncbi.nlm.nih.gov/pubmed/31217243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00505-19
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