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Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation

There is limited information about the molecular triggers leading to the uncoating of enteroviruses under physiological conditions. Using real-time spectroscopy and sucrose gradients with radioactively labeled virus, we show at 37°C, the formation of albumin-triggered, metastable uncoating intermedi...

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書目詳細資料
發表在:J Virol
Main Authors: Ruokolainen, Visa, Domanska, Aušra, Laajala, Mira, Pelliccia, Maria, Butcher, Sarah J., Marjomäki, Varpu
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694817/
https://ncbi.nlm.nih.gov/pubmed/31189702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00599-19
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