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Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its function i...

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Bibliografiske detaljer
Udgivet i:Crit Care
Main Authors: Ito, Takashi, Thachil, Jecko, Asakura, Hidesaku, Levy, Jerrold H., Iba, Toshiaki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694689/
https://ncbi.nlm.nih.gov/pubmed/31416465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2552-0
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