Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its function i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Crit Care
Hauptverfasser: Ito, Takashi, Thachil, Jecko, Asakura, Hidesaku, Levy, Jerrold H., Iba, Toshiaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694689/
https://ncbi.nlm.nih.gov/pubmed/31416465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2552-0
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