Restoration of primary cilia in obese adipose-derived mesenchymal stem cells by inhibiting Aurora A or extracellular signal-regulated kinase

BACKGROUND: Obesity impairs a variety of cell types including adipose-derived mesenchymal stem cells (ASCs). ASCs are indispensable for tissue homeostasis/repair, immunomodulation, and cell renewal. It has been demonstrated that obese ASCs are defective in differentiation, motility, immunomodulation...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Ritter, Andreas, Kreis, Nina-Naomi, Roth, Susanne, Friemel, Alexandra, Jennewein, Lukas, Eichbaum, Christine, Solbach, Christine, Louwen, Frank, Yuan, Juping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694567/
https://ncbi.nlm.nih.gov/pubmed/31412932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1373-z
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