Identifying Physical Causes of Apparent Enhanced Cyclization of Short DNA Molecules with a Coarse-Grained Model

[Image: see text] DNA cyclization is a powerful technique to gain insight into the nature of DNA bending. While the wormlike chain model provides a good description of small to moderate bending fluctuations, it is expected to break down for large bending. Recent cyclization experiments on strongly b...

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Udgivet i:J Chem Theory Comput
Main Authors: Harrison, Ryan M., Romano, Flavio, Ouldridge, Thomas E., Louis, Ard A., Doye, Jonathan P. K.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694408/
https://ncbi.nlm.nih.gov/pubmed/31282669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b00112
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