VRC01 in Acutely Treated HIV-infected Adults: A Randomised, Double-blind, Placebo-controlled Trial

BACKGROUND: HIV-1-specific broadly neutralizing antibodies such as VRC01 could promote HIV remission by halting viral replication and clearing infected cells. We conducted a randomised, double-blinded, placebo-controlled trial of VRC01 in adults who initiated antiretroviral therapy (ART) during acut...

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Pubblicato in:Lancet HIV
Autori principali: Crowell, Trevor A., Colby, Donn J., Pinyakorn, Suteeraporn, Sacdalan, Carlo, Pagliuzza, Amélie, Intasan, Jintana, Benjapornpong, Khunthalee, Tangnaree, Kamonkan, Chomchey, Nitiya, Kroon, Eugène, de Souza, Mark S., Tovanabutra, Sodsai, Rolland, Morgane, Eller, Michael A., Paquin-Proulx, Dominic, Bolton, Diane L., Tokarev, Andrey, Thomas, Rasmi, Takata, Hiroshi, Trautmann, Lydie, Krebs, Shelly J., Modjarrad, Kayvon, McDermott, Adrian B., Bailer, Robert T., Doria-Rose, Nicole, Patel, Bijal, Gorelick, Robert J., Fullmer, Brandie A, Schuetz, Alexandra, Grandin, Pornsuk V., O’Connell, Robert J., Ledgerwood, Julie E., Graham, Barney S., Tressler, Randall, Mascola, John R., Chomont, Nicolas, Michael, Nelson L., Robb, Merlin L., Phanuphak, Nittaya, Ananworanich, Jintanat
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693657/
https://ncbi.nlm.nih.gov/pubmed/31000477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3018(19)30053-0
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