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Structure of Heteropentameric GABA(A) Receptors and Receptor-Anchoring Properties of Gephyrin

γ-Aminobutyric acid type A receptors (GABA(A)Rs) mediate the majority of fast synaptic inhibition in the central nervous system (CNS). GABA(A)Rs belong to the Cys-loop superfamily of pentameric ligand-gated ion channels (pLGIC) and are assembled from 19 different subunits. As dysfunctional GABAergic...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Kasaragod, Vikram Babu, Schindelin, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693554/
https://ncbi.nlm.nih.gov/pubmed/31440140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00191
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