Modifications of the Transcriptomic Profile of Autoreactive B Cells From Pemphigus Patients After Treatment With Rituximab or a Standard Corticosteroid Regimen

Pemphigus Vulgaris is an autoimmune disease of the skin and mucous membranes, which is due to the production of pathogenic autoantibodies targeting desmoglein (DSG) 1 and 3, which are adhesion proteins of the keratinocytes. Rituximab is an anti-CD20 mAb which induces a prolonged depletion of blood B...

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Foilsithe in:Front Immunol
Main Authors: Hébert, Vivien, Petit, Marie, Maho-Vaillant, Maud, Golinski, Marie-Laure, Riou, Gaëtan, Derambure, Céline, Boyer, Olivier, Joly, Pascal, Calbo, Sébastien
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693356/
https://ncbi.nlm.nih.gov/pubmed/31440235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01794
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