Soluble fibrinogen-like protein 2 promotes the growth of hepatocellular carcinoma via attenuating dendritic cell-mediated cytotoxic T cell activity

BACKGROUND: Soluble fibrinogen-like protein 2 (sFGL2), a secretory protein expressed by regulatory T cells (Tregs) with immunosuppressive activity, is highly expressed in both the peripheral blood and tumor tissue of patients with hepatocellular carcinoma (HCC); however, sFGL2 function in HCC remain...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yang, Muyang, Zhang, Zhongwei, Chen, Jiajia, Xu, Mengying, Huang, Jiaquan, Wang, Ming, Li, Weina, Wan, Xiaoyang, Yuen, Man-Fung, Luo, Xiaoping, Xi, Dong, Ning, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693134/
https://ncbi.nlm.nih.gov/pubmed/31409352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1326-5
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