Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling

Human germinal center (GC)–associated lymphoma (HGAL) is an adaptor protein expressed in GC B cells. HGAL regulates cell motility and B-cell receptor (BCR) signaling, processes that are central for the successful completion of the GC reaction. Herein, we demonstrate phosphorylation of HGAL by Syk an...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Jiang, Xiaoyu, Lu, Xiaoqing, Zhang, Yu, Lacaria, Leda, Schuchardt, Brett J., Mikles, David C., Magistri, Marco, García-Ramírez, Idoia, Sanchez-Garcia, Isidro, Farooq, Amjad, Verdun, Ramiro E., Abdulreda, Midhat H., Moy, Vincent T., Lossos, Izidore S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693015/
https://ncbi.nlm.nih.gov/pubmed/31362927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018016162
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