Insights into determinants of spleen injury in sickle cell anemia

Spleen dysfunction is central to morbidity and mortality in children with sickle cell anemia (SCA). The initiation and determinants of spleen injury, including acute splenic sequestration (ASS) have not been established. We investigated splenic function longitudinally in a cohort of 57 infants with...

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Bibliographic Details
Published in:Blood Adv
Main Authors: El Hoss, Sara, Cochet, Sylvie, Marin, Mickaël, Lapouméroulie, Claudine, Dussiot, Michael, Bouazza, Naïm, Elie, Caroline, de Montalembert, Mariane, Arnaud, Cécile, Guitton, Corinne, Pellegrino, Béatrice, Odièvre, Marie Hélène, Moati, Frédérique, Le Van Kim, Caroline, Aronovicz, Yves Colin, El Nemer, Wassim, Brousse, Valentine
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2019
Subjects:
Red Cells, Iron, and Erythropoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693014/
https://ncbi.nlm.nih.gov/pubmed/31391165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000106
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