Thyroid Hormone Receptor β Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1–Dependent Chromatin Remodeling

Thyroid hormone receptor β (TRβ) suppresses tumor growth through regulation of gene expression, yet the associated TRβ-mediated changes in chromatin assembly are not known. The chromatin ATPase brahma-related gene 1 (BRG1; SMARCA4), a key component of chromatin-remodeling complexes, is altered in ma...

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Vydáno v:Endocrinology
Hlavní autoři: Gillis, Noelle E, Taber, Thomas H, Bolf, Eric L, Beaudet, Caitlin M, Tomczak, Jennifer A, White, Jeffrey H, Stein, Janet L, Stein, Gary S, Lian, Jane B, Frietze, Seth, Carr, Frances E
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2018
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692870/
https://ncbi.nlm.nih.gov/pubmed/29750276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00128
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