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Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Huntington's disease (HD) is a monogenic disorder, driven by the expansion of a trinucleotide (CAG) repeat within the huntingtin (Htt) gene and culminating in neuronal degeneration in the brain, predominantly in the striatum and cortex. Histone deacetylase 4 (Hdac4) was previously found to cont...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Federspiel, Joel D., Greco, Todd M., Lum, Krystal K., Cristea, Ileana M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692770/
https://ncbi.nlm.nih.gov/pubmed/31040226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.001253
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