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Multifaceted Mechanisms of Areca Nuts in Oral Carcinogenesis: the Molecular Pathology from Precancerous Condition to Malignant Transformation

Oral cancer is one of the most frequent malignant diseases worldwide, and areca nut is a primary carcinogen causing this cancer in Southeast Asia. It has been widely reported that areca nut induced several cytotoxic effects in oral cells, including ROS generation, inflammation, tissue hypoxia, DNA d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Li, Yi-Chen, Cheng, Ann-Joy, Lee, Li-Yu, Huang, Yu-Chen, Chang, Joseph Tung-Chieh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692602/
https://ncbi.nlm.nih.gov/pubmed/31417650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.29765
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