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How to assess the effectiveness of nasal influenza vaccines? Role and measurement of sIgA in mucosal secretions

Secretory IgAs (sIgA) constitute the principal isotype of antibodies present in nasal and mucosal secretions. They are secreted by plasma cells adjacent to the mucosal epithelial cells, the site where infection occurs, and are the main humoral mediator of mucosal immunity. Mucosally delivered vaccin...

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Detalhes bibliográficos
Publicado no:Influenza Other Respir Viruses
Main Authors: Gianchecchi, Elena, Manenti, Alessandro, Kistner, Otfried, Trombetta, Claudia, Manini, Ilaria, Montomoli, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692539/
https://ncbi.nlm.nih.gov/pubmed/31225704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/irv.12664
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