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A VNTR Regulates miR-137 Expression Through Novel Alternative Splicing and Contributes to Risk for Schizophrenia

The MIR137HG gene encoding microRNA-137 (miR-137) is genome-wide associated with schizophrenia (SZ), however, the underlying molecular mechanisms remain unknown. Through cloning and sequencing of individual transcripts from fetal and adult human brain tissues we describe novel pri-miR-137 splice var...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Pacheco, Ashley, Berger, Ralph, Freedman, Robert, Law, Amanda J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692358/
https://ncbi.nlm.nih.gov/pubmed/31409837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48141-0
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