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BMP-4 enhances epithelial mesenchymal transition and cancer stem cell properties of breast cancer cells via Notch signaling

Bone morphogenetic protein (BMP) signaling and Notch signaling play important roles in tumorigenesis in various organs and tissues, including the breast. BMP-4 enhanced epithelial mesenchymal transition (EMT) and stem cell properties in both mammary epithelial cell line and breast carcinoma cell lin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Choi, Sanghyuk, Yu, Jinyeong, Park, Aran, Dubon, Maria Jose, Do, Jungbeom, Kim, Youngjae, Nam, Donghyun, Noh, Jinok, Park, Ki-Sook
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692307/
https://ncbi.nlm.nih.gov/pubmed/31409851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48190-5
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